€ 19.99

USMLE Step 1 - uWorld High Yield Notes Exam 2023 | Questions and Answers

USMLE Step 1 - uWorld High Yield Notes Exam 2023 | Questions and Answers

What are the two major microtubular motor proteins? Which does anterograde axonal
transport, which does retrograde axonal transport? ------Correct Answer-------Kinesin,
Kinesin: Anterograde
Dynein: Retrograde`
What do you think, immunologically speaking, when you see someone with recurrent
Neisseria infections? ------Correct Answer-------Inability to form the membrane attack
(MAC) complex
this is a common complement deficiency
What is the defect in Chronic Granulomatous disease? What is the pathophysiology? ---
---Correct Answer-------NADPH Oxidase deficiency leads to the inability to kill
intracellular organisms
Characteristic triad of ataxia telangiectasia? ------Correct Answer-------cerebellar ataxia,
telangiectasias, increased risk of sinopulmonary infections
What is the major immune deficiency of ataxia telangiectasia? ------Correct Answer-------
IgA deficiency, which predisposes to infections of the upper and lower airways (and
other mucous membranes)
There's a useful mnemonic for Ataxia Telangiectasia and the gene that's mutated. What
is it? ------Correct Answer-------ATM
ATM gene is responsible for DNA break repair
What is one reason that lead intoxication causes hypochromic anemia? ------Correct
Answer-------Mitochondrial iron transport is important for Heme synthesis! It's inhibited
by lead. So you don't make heme in your mitochondria and you get hypochromic
What is the biochemical problem in Lesch-Nyhan syndrome? (And, only if you got that
right, what are the really cool symptoms of it?) ------Correct Answer-------Defective
purine catabolism, so buildup of purines. It's an X-linked recessive disorder with
mutated HGPRT gene (hypoxanthine-guanine phosphoribosyltransferase, if you want to
impress people).

Preview document (3 of 37 pages)

Unlock document

Download all 37 pages for € 19,99

Add document to cart
Report document Report document

Knoowy benefits

€ 19,99

Add document to cart
  • check Money back guarantee
  • check Documents can be downloaded immediately
  • check € 0,50 discount when paying with balance
  • check Receive free quiz questions with document



Study Help

265 documents uploaded

4 documents sold

This account provides quality exam questions, answers, study guides, and flashcards. All the best!!!

Earn from your summaries?

icon 2

Do you make summaries or do you have any completed assignments? Upload your documents to Knoowy and earn money.

Upload document
Log in via e-mail
New password
Subscribe via e-mail
Sign up via Facebook
Shopping cart

Deal: get 10% off when you purchase 3 or more items!

Deal: get 10% off when you purchase 3 or more items!

[Inviter] gives you € 2.50 to purchase summaries

At Knoowy you buy and sell the best studies documents directly from students. <br> Upload at least one item, please help other students and get € 2.50 credit.

Register now and claim your credit