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NBME CBSE REAL EXAM 200 QUESTIONS AND ANSWERS LATEST (usmle step 1)MEDICAL EXAMINATION

NBME CBSE REAL EXAM 200 QUESTIONS AND ANSWERS LATEST (usmle  step 1)MEDICAL EXAMINATION

NBME CBSE REAL EXAM 200 QUESTIONS AND ANSWERS LATEST (usmle
step 1)MEDICAL EXAMINATION
What is a case series? - AnswersDescription of clinical findings/symptoms for several patients with the
same diagnosis, treatment, or outcome.
What is a cross-sectional study? - AnswersAssesses the frequency of disease and risk-related factors in
the present.
What is a case-control study? - AnswersRetrospectively compares a group of people with a disease to a
group without the disease to determine if odds of prior exposure/risk factor differ.
What is a cohort study? - AnswersCompares a group of people with a given exposure/risk factor to a
group without exposure to determine if the exposure/risk factor is associated with later development of
disease.
What is a twin concordance study? - AnswersCompares the frequency with which both monozygotic
twins vs both dizygotic twins develop the same disease to measure heritability and influence of
environmental factors.
What is an adoption study? - AnswersCompares behavioral traits/genetics in siblings raised by biological
vs adoptive parents to measure heritability and influence of environmental factors.
What is an ecological study? - AnswersCompares the frequency of disease and risk-related factors across
populations to measure population data (not applicable to individuals).
What is a clinic therapeutic trial? - AnswersAn experimental study involving humans that compares the
benefits of two or more interventions.
What are the criteria for a high-quality clinical trial? - AnswersRandomized, controlled, and doubleblinded
What is a crossover clinical trial? - AnswersCompares the effect of multiple treatments on a subject
What is the purpose of randomizing the order of treatments in a crossover trial? - AnswersTo avoid bias
What is a washout period in a crossover trial? - AnswersA period between treatments to eliminate any
lingering effects
What is the advantage of using a crossover trial? - AnswersSubjects serve as their own controls
What is the intention-to-treat analysis? - AnswersAnalyzing all subjects according to their original
assigned treatment
What is the purpose of intention-to-treat analysis? - AnswersTo avoid bias from attrition, crossover, and
noncompliance
What is the disadvantage of intention-to-treat analysis? - AnswersMay dilute the true effects of the
intervention
What is the as-treated analysis? - AnswersAnalyzing subjects according to the treatment they actually
received
What is the disadvantage of as-treated analysis? - AnswersIncreases the risk of bias
What is the per-protocol analysis? - AnswersExcluding subjects who did not complete the originally
assigned treatment

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