Must Knows on Local Anesthetics

A study guide on local anesthetics which is intended for pharmacology, nursing and medicine students. Lidocaine is a prototype amino-amide type of amino anesthetics. Local anesthesia only penetrates the Nodes of Ranvier where Na+ channels are concentrated. Bupivacaine is most commonly used for local infiltration, spinal and epidural anesthesia. Lidocaine is most commonly used local anesthesia with wide variety of uses which is relatively free of allergic reactions.